| A
60-year-old man with a past history of controlled hypertension presents
with acute onset weakness of his left arm, that resolved over 12 hours. He
had suffered two similar episodes over the last three months. Examination
reveals a blood pressure of 132/82 mmHg and he is in atrial fibrillation
with a ventricular rate of 85 per minute. CT brain scan is normal.
What
is the most appropriate management?
- Amiodarone
- Digoxin
- Aspirin
- Dypyridamole
- Warfarin
Answer
|
A 28-year-old man who is known to have
Hypertrophic Cardiomyopathy has an out of hospital cardiac arrest and is
successfully resuscitated. What is the most appropriate mode of treatment?
- Alcohol
septal ablation
- Amiodarone
- beta
blocker
- implantable
defibrillator
- myomectomy
Answer
|
A 35-year-old healthy woman has a faint systolic
murmur on physical examination. An echocardiogram is performed, and she is
found to have a bicuspid aortic valve. In explaining the meaning of this
finding to her, the most appropriate statement is that?
- An
aortic valve replacement is eventually likely to be required
- Other
family members are likely to have the same condition
- She
should be treated with a cholesterol lowering agent
- The
problem resulted from past injection drug usage
- This
is one manifestation of an underlying autoimmune condition
Answer
|
A
27 year old woman complained of palpitations, breathlessness and chest
pain, radiating to the left arm. These symptoms had developed six weeks
previously, after she had witnessed her father dying from a myocardial
infarction. In the past 10 years she had been investigated for abdominal
pain, headaches, joint pains, and dyspareunia, without serious cause being
found for these symptoms.
What
is the most likely diagnosis?
- depressive episode
- factitious disorder
- generalized anxiety disorder
- hypochondriasis
- somatization disorder
Answer
|
| A
65 year old male with left ventricular systolic dysfunction was dyspnoeic
on climbing stairs but not at rest. The patient was commenced on Ramipril
and Furosemide.
Which
one of the following drugs would improve the patient’s prognosis
further?
- Amiodarone
- digoxin
- diltiazem
- Metoprolol
- Isosorbide dinitrate
Answer
|
Primary prevention trials for the treatment of
hypercholesterolaemia reveal a reduction in all cause mortality following
treatment with which of the following?
- fibrates
- fish
ols
- nicotinic
acid
- resins
- statins
Answer
|
A 69 year old man is treated for chest infection.
He has been on a stable dose of warfarin for the last six months as a
treatment for atrial fibrillation, with INR recordings between 2-2.5.
However, his most recent INR was 5. Which one of the following drugs that
has recently been started is likely to be responsible for the increased
INR.
- Clarithromycin
- Co-dydramol
- Digoxin
- Rifampicin
- Temazepam
Answer
|
A
74-year-old man presented with acute pain, pallor and absent pulses in his
right leg. Investigations revealed an embolus in his femoral artery.
What
is the most likely source of this embolus?
- Marantic
endocarditis
- paradoxical
emboli
- rheumatic
endocardial vegetations
- right
ventricular thrombi
- thrombi
from atheromatous aorta
Answer
|
|
A
72-year-old man presents with an episode of collapse. He has had two
similar episodes recently, each lasting about one minute. Four years ago
he suffered an anterior myocardial infarction.
On examination he
was orientated and symptom-free with a regular pulse rate of 80 bpm, BP
140/80 mmHg and the apex beat was displaced to the left. There was an
apical systolic murmur. There were no signs of trauma. ECG showed sinus
rhythm, Q waves and ST segment elevation anteriorly without reciprocal
depression.
What
is the diagnosis?
- acute anterior myocardial infarction
- cerebrovascular accident
- epileptic seizure
- pulmonary embolism
- ventricular tachycardia
Answer
|
Left atrial myxoma may be associated with all
except-
- sudden
death
- a
mid systolic click
- systemic
emboli
- left
atrial dilatation
- adrenal
hyperplasia
Answer
|
Which one of the following is the most likely
mechanism by which Aspirin exerts its beneficial effects in patients with
coronary artery disease?
- anti
inflammatory action
- cyclo
oxygenase inhibition
- glycoprotein
IIB/IIIA receptor inhibition
- inhibition
of binding of adenosine diphosphonate to its platelet receptor
- structural
changes in platelets
Answer
|
A 57-year-old female school cleaner is
undergoing investigation for breathlessness. All the following would be in
keeping with a diagnosis of constrictive pericarditis except
- elevated
JVP with absent y descent
- peripheral
oedema
- orthopnea
- ascites
- previous
cardiac surgery
Answer
|
A study reveals an immediate rise in blood
pressure following infusion of a hormone in normal volunteers. Which of
the following is the most likely hormone used in this study?
- angiotensin
I
- angiotensin
II
- atrial
natriuretic peptide
- brain
natriuretic peptide
- prolactin
Answer
|
A 55-year-old woman has had worsening
shortness of breath for several years. She now has to sleep sitting up on
two pillows. She has difficulty swallowing. There is no history of chest
pain. She is afebrile. Recently, she suffered a stroke with left
hemiparesis. A chest X-ray reveals a near-normal left ventricular size
with a prominent left atrial border. Which of the following conditions is
most likely to account for these findings?
- aortic
coarctation
- cardiomyopathy
- essential
hypertension
- left
renal artery stenosis
- mitral
valve stenosis
Answer
|
A 72 year old man noted to have a systolic
murmur undergoes an echocardiogram which demonstrates aortic stenosis.
Which of the following is associated with a poor prognosis in this
patient?
- aortic
regurgitation
- cardiomegaly
on chest Xray
- clinical
features of left ventricular failure
- ECG
evidence of left ventricular hypertrophy
- severe
valvular calcification on echocardiography
Answer
|
A 42 year old male admitted with dyspnoea is
noted to have a murmur suggestive of mitral stenosis. The presence of
which of the following clinical signs suggests that the mitral valve is
mobile?
- fourth
heart sound
- loud
second heart sound
- opening
snap
- a
soft first heart sound
- a
third heart sound
Answer
|
A 44-year-old man has had no major medical
problems throughout his life, except for arthritis pain involving all
extremities for the past couple of years. He has had worsening orthopnoea
and ankle oedema in the past six months. He is afebrile. There is no chest
pain. A chest X-ray shows cardiomegaly with both enlarged left and right
heart borders, along with pulmonary oedema. Laboratory test findings
include sodium 139 mmol/L, potassium 4.3 mmol/L, urea 7 mmol/L creatinine
95 µmol/L, and glucose 8.6 mmol/L. Which of the following additional
laboratory test findings is he most likely to have?
- anticentromere
antibody titre of 1:320
- erythrocyte
sendimentation rate of 79 mm/ hr
- hemoglobin
of 10.7 g/dl with MCV of 72fL
- serum
ferritin of 3400 micromole/L
- spherocytes
in his peripheral blood smear
Answer
|
Which ONE of the following statements is true
about the diastolic Austin Flint murmur?
- it
is associated with a loud first heart sound
- it
is an early sign of aortic regurgitation
- it
can be distinguished from the murmur of mitral stenosis by absence of
presystolic accentuation
- it
is due to partial closure of the anterior leaflet of the mitral valve
- it
does not occur in aortic incompetence secondary to an aortitis
Answer
|
Which ONE of the following is a
contraindication to thrombolysis?
- age
over 75 years
- the
presence of atrial fibrillation
- asthma
- pregnancy
- background
diabetic retinopathy
Answer
|
Cyanosis is a typical feature of which of the
following conditions
- patent
ductus arteriosus
- ventricular
septal defect
- total
anomalous pulmonary venous drainage
- atrial
septal defect
- mitral
atresia
Answer
|