Back to main page

DERMATOLOGY Questions  1   2   3   

Which of the following statements regarding Psoriasis is most true? 

  1. diagnosis requires histological confirmation

  2. Gutatte psoriasis often arises after staphylococcal infection

  3. T cells play a prominent role in the pathogenesis of psoriasis

  4. cyclosporin is ineffective in the treatment of psoriasis

  5. twin studies have identified no genetic basis of psoriasis


A 40-year-old man presented with pityriasis versicolor.

What is the most appropriate treatment?

  1. methotrexate

  2. oral terbinafine

  3. psoralen with ultraviolet light (PUVA) therapy

  4. topical selenium sulphide

  5. phototherapy with ultraviolet light (UVB)



Deficiency of which one of the following trace elements is implicated as a cause of cardiomyopathy? 

  1. chromium

  2. copper

  3. manganese

  4. selenium

  5. zinc


A previously fit, 30-year-old female presents with a four day history of intractable pruritus and urticaria. What is the most appropriate initial management? 

  1. chlorpheniramine

  2. prednisolone

  3. ranitidine

  4. topical hydrocortisone

  5. topical mepyramine


A 55 year old woman presents with a non-pruritic rash that had developed over the last two months. Examination revealed several, circular, erythematous, raised, smooth-surfaced lesions of variable size from 1 – 5 cms in diameter on the elbows, extensor aspects of the forearms and knuckles.

What is the most likely diagnosis?

  1. eczema

  2. granuloma annulare

  3. psoriasis

  4. tinea corporis

  5. urticaria


A 50-year-old man presented in the summer complaining of itching and blistering of his hands and forehead. On examination there were small areas of excoriation on the backs of his hands. What is the most likely diagnosis? 

  1. dermatitis herpetiformis

  2. lupus erythematosis

  3. pemphigoid

  4. pemphigus

  5. porphyria cutanea tarda


A 22 year old male presents with generalised pruritus of six weeks duration. Examination reveals little except for erythematous papules between the fingers. Which ofthe following therapies would be most appropriate for this patient? 

  1. astemizole

  2. calamine lotion

  3. chlorpromazine

  4. ciprofloxacin

  5. permethrin cream


A 24 year old female presents with vague frontal headaches and visual disturbance. She has a past history of acne for which she is receiving treatment. Examination reveals her to be obese with a blood pressure of 110/70 mmHg. There is absence of the central retinal vein pulsation on fundoscopic examination. Which of the following drugs account for these findings? 

  1. isotretinoin

  2. ampicillin

  3. topical tetracycline

  4. dianette

  5. erythromycin


A 15 year-old boy was treated with permethrin cream for scabies infestation. On follow-up three weeks later, he was found to have continuing infestation. What is the most likely reason for this? 

  1. the treatment was not repeated as prescribed

  2. other household members were not treated

  3. facial skin was not treated

  4. non-disposal of underwear

  5. the organism is resistant to permethrin


A 75-year-old female presents with chronic leg ulceration which is a consequence of venous insufficiency.

Which one of the following is the most appropriate management?

  1. appropriate systemic antibiotic in preparation for skin grafting

  2. compression bandaging

  3. improve the venous return by limb elevation

  4. skin biopsy to exclude neoplasm

  5. vein surgery 


Exposure to sunlight aggravates 

  1. pellagra

  2. acne vulgaris

  3. psoriasis

  4. acute intermitent porphyria

  5. xeroderma elasticum


What is the most common presenting feature of porphyria cutanea tarda? 

  1. acute blistering crises affecting the trunk and limbs

  2. acute redness and swelling following sun exposure

  3. erythroderma

  4. generalised hypertrichosis

  5. skin fragility and blistering affecting the hands, face and scalp


A 43 year old woman with atopic dermatitis (atopic eczema) presented with an acute generalized exacerbation of her disease. She was admitted to hospital but failed to improve with emollients, topical betamethasone-17-valerate and oral antihistamine. Which one of the following drugs is the most appropriate treatment? 

  1. acitretin

  2. amoxycillin

  3. cyclosporin

  4. colchicine

  5. dapsone


Which of the following suggests a diagnosis of molluscum contagiosum rather than chickenpox? 

  1. presence of macules and papules

  2. absence of erythema surronding lesions

  3. lesions disappearing within a month

  4. presence of pruritus

  5. positive contact history


Which of the following is a recognised feature of psoriasis? 

  1. angular stomatitis

  2. iridocyclitis

  3. Koebner Phenomenon

  4. loss of hair

  5. response to chloroquine


Which of the following is a true of cutaneous anthrax? 

  1. causes a black eschar which overlies pus

  2. lesions are usually painful and tender

  3. lesions are associated with marked oedema

  4. mortality is approximately 20% despite antibiotic therapy

  5. is very likely to occur in subjects exposed to anthrax spores


In the treatment of psoriasis, which of the following statements is correct? 

  1. PUVA is ineffective

  2. retinoids are the most useful monotherapy in psoriatic patients

  3. etanercept is not effective in psoriasis

  4. infliximab is associated with tuberculosis

  5. vitamin D analogues are associated with cutaneous atrophy


A 68-year-old woman presents with a 2 month history of a widespread pruritic rash. Examination reveals widespread erythema with several small blisters containing straw-coloured fluid and one or two larger serosanguinous blisters. What is the most likely diagnosis? 

  1. bullous impetigo

  2. bullous pemphigoid

  3. insect bite

  4.  scabies

  5. urticarial vasculitis


A 65 year old female who has a history of longstanding psoriasis and heavy alcohol intake, presents with a severe exacerbation of psoriasis. She was admitted and received topical therapy and over the month of her admission, her gamma-GT concentration had fallen from 400 U/L to 150 U/L (4 - 35). Six weeks after discharge she was seen in outpatients where her psoriasis remained under control, but she complained of generalized hair loss. What is the most likely cause for her hair loss? 

  1. alopecia areata

  2. iron deficiency

  3. telogen effluvium

  4. thiamine deficiency

  5. trichotilomania


A 60 year old woman presents with raised, erythematous lesions on the limbs and blistering in the mouth and eyes. She had been taking a number of drugs prescribed by her GP. Which may be responsible for her presentation? 

  1. nifedipine

  2. paracetamol

  3. paroxetine

  4. prednisolone

  5. sulphasalazine





Copyright © ** - All Rights Reserved
Design Template by Web Design Studio
Basic Sciences
Infectious Disease